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– ContinuousInfusion. Label: AFM Records, Inc. – AFM5FU-081597-1.
Original Articles MMPR Infusion, 5-F Infusion. Fourty-four evaluable patients were treated with ne riboside (MMPR) at a dose of 20 mg/m2/day x 5 by continuous IV infusion (days 1–5) and 5-fluorouracil (5-FU) on an escalating dose schedule of 300–1519 mg/m2/day x 5 by continuous IV infusion (days 2–6). Cancer Treat Rep 66:299–303Google Scholar. Cancer Chemother Pharmacol 8:301–304Google Scholar.
The infusion system consists of two Horizon Nxt infusion pumps, a on valve and a sterile 50 ml vial. The variation of the production of H2O was < 1%. The activity delivered as measured by scanner counts varied < 2% during the steady state period. The system has been demonstrated to be capable of delivering activity over a wide range of conditions. Authors: M Sajjad; J S Liow; J Moreno-Cantu.
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Continuous infusion of ifosfamide was generally well tolerated and useful for palliation in 10 of 25 patients. A higher dose intensity is recommended. Continuous 5-day infusion of ifosfamide with mesna in inoperable pancreatic cancer patients : a phase II study.
The dose-limiting toxicities were hand-foot syndrome and severe mucositis. A response rate of 21% and 50% stable disease could be achieved.
Continuous Transarterial Infusion Chemotherapy with Gemcitabine. Integris 3000 DSA system). Target arteries of cancer were. evaluated according to World Health Organization (WHO) solid tumor effectiveness judgment. This study was performed to determine the activity of adding continuous infusion (CI) of 5-fluorouracil (5-FU) to gemcitabine (GEM) vs GEM alone in advanced pancreatic cancer (APC). In all, 94 chemo-naı¨ve patients with APC were randomised to receive GEM alone (arm A: 1000 mg m2 per week for 7 weeks followed by a 2 week rest period, then weekly for 3 consecutive weeks out of every 4 weeks) or in combination with CI 5-FU (arm B: CI 5-FU 200 mg m2 day1 for.
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